{"created":"2023-05-15T12:15:49.020419+00:00","id":201,"links":{},"metadata":{"_buckets":{"deposit":"4e237790-4da4-436e-ba13-95fa0f7da62e"},"_deposit":{"created_by":2,"id":"201","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"201"},"status":"published"},"_oai":{"id":"oai:sakuranoseibo.repo.nii.ac.jp:00000201","sets":["1:55"]},"author_link":["458","459"],"control_number":"201","item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-03-31","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"46","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"桜の聖母短期大学紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"BULLETIN OF SAKURA NO SEIBO JUNIOR COLLEGE","bibliographic_titleLang":"en"}]}]},"item_10002_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"pdf","subitem_description_type":"Other"}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"マクロファージは「白血球」に分類される細胞の一つで、細菌やウイルスの感染から生体を防御する免疫担当細胞として極めて重要な役割を担っている。一方で、食事成分やさまざまな生活習慣の影響により、マクロファージ機能が病的な方向に制御されると、動脈硬化を起因とする心血管疾患、脳血管疾患やがんなど様々な疾病を引き起こすことも明らかとなっている。この病的なマクロファージの機能を、種々の食品成分によって調節し、正常化できる可能性が近年数多く報告されてきている。本稿では、食品成分によるマクロファージ機能の調節を通して、生活習慣病などさまざまな疾病の予防・改善を行える可能性について、最新の知見を交えて論じる。\nMacrophages are the cells classified as “white blood cells” and play important roles as immunocompetent cells that protect the organism from foreign substances such as bacteria and viruses. On the other hand, when macrophage function is controlled in a pathological direction by the influence of dietary components and various lifestyles, it causes various diseases such as cardiovascular disease, cerebrovascular disease caused by arteriosclerosis, and cancers. In recent years, many reports have been made on the possibility that the function of this pathological macrophage can be regulated and normalized by various food components. In this review, I will discuss the possibility of preventing and improving various diseases such as lifestyle-related diseases by the regulation of macrophage function using food components, together with the latest findings.","subitem_description_type":"Abstract"}]},"item_10002_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24796/00000188","subitem_identifier_reg_type":"JaLC"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"桜の聖母短期大学"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN10531157","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386－8168","subitem_source_identifier_type":"ISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"梶谷, 宇","creatorNameLang":"ja"},{"creatorName":"カジタニ, タカシ"}],"nameIdentifiers":[{"nameIdentifier":"458","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Takashi, Kajitani","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"459","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-06-07"}],"displaytype":"detail","filename":"No46-1.pdf","filesize":[{"value":"431.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"No46-1.pdf","url":"https://sakuranoseibo.repo.nii.ac.jp/record/201/files/No46-1.pdf"},"version_id":"431ec933-1560-412e-b82d-504064e55fce"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Macrophage","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Inflammation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Food Components","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Healthy Life Expectancy","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"食品成分でのマクロファージ機能制御による疾病予防・改善の可能性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"食品成分でのマクロファージ機能制御による疾病予防・改善の可能性","subitem_title_language":"ja"},{"subitem_title":"Potential preventive and therapeutic effects of regulating macrophage function by food components","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"2","path":["55"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-06-07"},"publish_date":"2022-06-07","publish_status":"0","recid":"201","relation_version_is_last":true,"title":["食品成分でのマクロファージ機能制御による疾病予防・改善の可能性"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-06-21T05:39:49.294516+00:00"}